Type II cells isolated from the rat lung were maintained in culture for 8 d
ays. The activity of alkaline phosphatase and lectin binding properties wer
e studied. The alkaline phosphatase activity and the number of lamellar bod
ies were continually decreasing during the studied time period. The profile
of lectin binding (Maclura pomifera and Ricinus communis) did not change d
uring the cultivation.