Despite the cause of formation of antibodies in the dam against parts of er
ythrozyte membran of the lamb could not be verified it is remarkable that a
lso sheep lambs may suffer from neonatal isoerythrolysis in rare cases. Due
to the clinical signs and laboratory parameter the disease is relatively r
eliable to diagnose. The diagnosis of neonatal isoerythrolysis was confirme
d using a appropriate serodiagnostic investigation. The intensively and ear
ly started therapy resulted in a improvement of the clinical status of the
lamb within 24 hours. The further development of the lamb after recovering
from the disease was undisturbed.