Injuries to the central venous system can result from penetrating trauma or
iatrogenic causes. Injuries to major venous confluences can be particularl
y problematic, because the clavicle and sternum seriously limit exposure of
the injury site. We report our institution's experience with central venou
s injuries of the subclavian-jugular and innominate-caval venous confluence
s. Significant injuries of the subclavian-jugular venous confluence frequen
tly result from penetrating trauma, while injuries to the innominate-caval
confluence are usually catheter-related. Median sternotomy provides adequat
e exposure of the innominate-caval confluence while exposure of the subclav
ian-jugular venous confluence requires extension of the median sternotomy i
ncision into the neck and resection of the clavicle. The literature is revi
ewed.