K. Sarica et al., Unilateral testicular torsion: Protective effect of verapamil on contralateral testicular histology, UROL INTERN, 62(3), 1999, pp. 159-163
In this experimental study, it was our aim to reduce the effects of ischemi
c insults to the contralateral testicle after unilateral testicular torsion
. The protective effect of a calcium channel blocking agent (verapamil) on
the histology and the tubular diameter of contralateral testicle was evalua
ted, Following a definite period of unilateral testicular torsion (i.e., 4
h), the protective effect of this specific medication was evaluated both af
ter detorsion and orchiectomy procedures, The results of our study demonstr
ated the protective effect of verapamil on both parameters, especially in a
nimals undergoing orchiectomy. The majority of the specimens demonstrated n
ormal histologic findings together with preserved tubular structures after
a 1-week period under verapamil medication.