Unilateral testicular torsion: Protective effect of verapamil on contralateral testicular histology

Citation
K. Sarica et al., Unilateral testicular torsion: Protective effect of verapamil on contralateral testicular histology, UROL INTERN, 62(3), 1999, pp. 159-163
Citations number
23
Categorie Soggetti
Urology & Nephrology
Journal title
UROLOGIA INTERNATIONALIS
ISSN journal
00421138 → ACNP
Volume
62
Issue
3
Year of publication
1999
Pages
159 - 163
Database
ISI
SICI code
0042-1138(1999)62:3<159:UTTPEO>2.0.ZU;2-M
Abstract
In this experimental study, it was our aim to reduce the effects of ischemi c insults to the contralateral testicle after unilateral testicular torsion . The protective effect of a calcium channel blocking agent (verapamil) on the histology and the tubular diameter of contralateral testicle was evalua ted, Following a definite period of unilateral testicular torsion (i.e., 4 h), the protective effect of this specific medication was evaluated both af ter detorsion and orchiectomy procedures, The results of our study demonstr ated the protective effect of verapamil on both parameters, especially in a nimals undergoing orchiectomy. The majority of the specimens demonstrated n ormal histologic findings together with preserved tubular structures after a 1-week period under verapamil medication.