Sequestrum-like appearance of a multiple sclerosis brain lesion on serial magnetic resonance images

Using serial magnetic resonance imaging, we monitored an unique lesion of t he brain in a 15-year-old girl with clinically definite and laboratory-supp orted remitting-relapsing multiple sclerosis. During initial phases of the disease course, cystic necrosis around the plaque was observed Later, remye lination of the central core of the lesion was speculated, as similarities in signal intensity between the core and the normal appearing white matter were partially recovered both on the T1- and the T2-weighted images.