Various N-aryl-4-phenyl-3-(4-phenoxyphenyl)butanamides (2 and 3) were teste
d for fungicidal activities against Pyricularia oryzae, Rhizoctonia solani,
Botrytis cinerea, Phytophthora infestans, Puccinia recondita, and Erysiphe
graminis in vivo. Butanamides (2 and 3a) that have an electron withdrawing
group (Cl, F) attached to the meta position of the phenyl ring showed good
to excellent activities against Pyricularia oryzae, Puccinia recondita, an
d Erysiphe graminis in high concentration while those that have a strong el
ectron withdrawing group (CN, NO2) or electron donating group (OCH3, CH3) a
ttached to the meta position did not show good activities against all test
fungi at 250 mg L-1. The antifungal; activities of the compounds synthesize
d were compared with reference compounds such as Tricyclazole, Moncozeb, an
d Benomyl.