Synthesis of novel orthoalkylaminophenol derivatives as potent neuroprotective agents in vitro.

Citation
R. Larget et al., Synthesis of novel orthoalkylaminophenol derivatives as potent neuroprotective agents in vitro., BIOORG MED, 9(20), 1999, pp. 2929-2934
Citations number
24
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
20
Year of publication
1999
Pages
2929 - 2934
Database
ISI
SICI code
0960-894X(19991018)9:20<2929:SONODA>2.0.ZU;2-3
Abstract
A series of orthoalkylaminophenol derivatives was synthesized and tested in vitro with respect to their neuroprotective effect. Some of these compound s exhibited a potent antioxidant activity close to that of standard alpha-t ocopherol. (C) 1999 Elsevier Science Ltd. All rights reserved.