A new approach to the synthesis of efaroxan

Authors
Couture, K Gouverneur, V Mioskowski, C
Citation
K. Couture et al., A new approach to the synthesis of efaroxan, BIOORG MED, 9(20), 1999, pp. 3023-3026
Citations number
18
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
20
Year of publication
1999
Pages
3023 - 3026
Database
ISI
SICI code
0960-894X(19991018)9:20<3023:ANATTS>2.0.ZU;2-1
Abstract
Efaroxan was synthetised by cyclisation of the tertiary alcohol 2 which was prepared by the ring opening of the gem-disubstituted epoxide 3 with ortho -metallated fluorobenzene. (C) 1999 Elsevier Science Ltd. All rights reserv ed.