OBJECTIVE To assess whether advance directives influence resource use by ho
spitalized patients.
DATA SOURCES A systematic search of computerized medical databases, referen
ce lists from relevant articles, and personal files was conducted to identi
fy studies examining the association between advance directives and resourc
e use.
STUDY SELECTION Primary studies assessing the effect of advance directives
on hospital resource use were selected if they had a clear quantitative mea
sure of hospital resource use, hospitalized patients as a study population,
a control group for comparison, and a description of the advance directive
being studied. Data on the following topics were abstracted from studies m
eeting inclusion criteria: study methods and design, resource use, source o
f financial data, description of advance directive, population size and com
position, length of assessment.
SYNTHESIS Six studies met inclusion criteria. Three retrospective studies s
howed significant reductions in resource use associated with documentation
of advance directives while three prospective studies (two randomized, one
not randomized) showed no association between advance directives and reduce
d resource use. Studies were limited to narrowly defined patient population
s in US tertiary care hospitals.
CONCLUSIONS Little evidence supports the hypothesis that advance directives
reduce resource use by hospitalized patients. Some retrospective studies h
ave shown savings, but their conclusions are weakened by shortcomings in st
udy design. Prospective trials, which have better experimental methods, hav
e demonstrated no evidence of cost savings with the use of advance directiv
es.