Cytogenetic investigation of transitional cell carcinomas of the upper urinary tract

Authors
Dal Cin, P Roskams, T Van Poppel, H Balzarini, P Van den Berghe, H
Citation
P. Dal Cin et al., Cytogenetic investigation of transitional cell carcinomas of the upper urinary tract, CANC GENET, 114(2), 1999, pp. 117-120
Citations number
22
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
CANCER GENETICS AND CYTOGENETICS
ISSN journal
01654608 → ACNP
Volume
114
Issue
2
Year of publication
1999
Pages
117 - 120
Database
ISI
SICI code
0165-4608(19991015)114:2<117:CIOTCC>2.0.ZU;2-P
Abstract
Cytogenetic investigation was attempted on 44 tumors from 44 patients with transitional cell carcinoma (TCC) of the upper urinary tract (pelvis and ur eter), and karyotypes were obtained in 27 tumors. Numerical changes prevail ed, but are not specific for this type of tumor (trisomy 7 -Y, or both). In the light of previously reported data on TCC, the finding of a del(9q) as the only anomaly in one of the cases may be meaningful. Patients showing -Y and/or trisomy 7 had a poor prognosis. (C) Elsevier Science Inc., 1999. Al l rights reserved.