Palladium-catalyzed terminal alkyne coupling reaction of beta-bromo-beta-phenylthio or beta-methylthio-alpha-trifluoromethyl enol ethers: a convenient synthesis of 2-sulfonyl-1-buten-3-ynes
M. Yoshimatsu et al., Palladium-catalyzed terminal alkyne coupling reaction of beta-bromo-beta-phenylthio or beta-methylthio-alpha-trifluoromethyl enol ethers: a convenient synthesis of 2-sulfonyl-1-buten-3-ynes, CHEM PHARM, 47(10), 1999, pp. 1497-1500
2-Sulfonyl-1-buten-3-yne (2-sulfonyl enyne)7 was obtained via the Pd-cataly
zed cross-coupling reactions of beta-bromo enol ethers 3 and 4 and successi
ve oxidation with m-chloroperbenzoic acid.