Growth of newborn, term infants fed soy formulas for 1 year

Few studies have measured long-term growth in infants fed soy protein-based formulas. The effect of nucleotide (NT) supplementation of soy protein-bas ed infant formulas on growth is unknown. Growth was therefore evaluated in healthy term infants fed a soy protein-based formula (SOY; n=73), SOY with added NT (72 mg added NT/L) at human milk (HM) levels (SOYN: n=73), or mixe d feeding (MF, n=67) in a randomized, masked, parallel 1-year feeding study The MF group (a nonrandomized reference group) was fed HM exclusively from birth to 2 months of age followed by HM and/or a standard milk-based formu la (Similac(R) with Iron with no supplemental NTs) to 1 year of ag-e. Resul ts indicated that growth (weight, length, and head circumference) was norma l and comparable among the three groups. All three groups had similar plasm a albumin (at 2 months of age) and hemoglobin levels (at 12 months of age). Thus, this study demonstrated similar growth in the first year of life amo ng infants fed MF feeding or soy formula with or without supplemental NTs.