Paracheirodon innesi was exposed (simultaneously or sequentially) to copper
and lead in varying concentrations in a synthetic water solution. Metal ac
cumulations in fish gills and the fish (without gills) were measured at the
end of the exposure period. Results of the exposure experiment indicated t
hat lead seems to facilitate the uptake of copper and vice versa when the e
xposure process is simultaneous. In the case of sequential exposure first t
o copper for 7 days then to lead for 20 days, lead accumulations in the fis
h and the gills were enhanced by copper, indicating a possible alteration o
f the physiological absorption process. The synergistic effects observed du
ring either simultaneous or sequential exposure experiments can be describe
d using logistic equations. (C) 1999 Academic Press.