Recent outbreaks of Salmonella and Escherichia coli O157:H7 infections asso
ciated with raw seed sprouts have occurred in several countries. Subjective
evaluations indicate that pathogens can exceed 10(7) per gram of sprouts p
roduced from inoculated seeds during sprout production without adversely af
fecting appearance. Treating seeds and sprouts with chlorinated water or ot
her disinfectants fails to eliminate the pathogens. A comprehensive approac
h based on good manufacturing practices and principles of hazard analysis a
nd critical control points can reduce the risk of sprout-associated disease
. Until effective measures to prevent sprout-associated illness are identif
ied, persons who wish to reduce their risk of foodborne illness from raw sp
routs are advised not to eat them; in particular, persons at high risk for
severe complications of infections with Salmonella or E. coli O157:H7, such
as the elderly, children, and those with compromised immune systems, shoul
d not eat raw sprouts.