Selective ablation of porcine and rabbit liver tissue using radiofrequency: Preclinical study

Authors
Nakagawa, A Kamiyama, Y Matsui, Y Nakagawa, N Araki, H Kasamatsu, S Wei, T Okuda, Y Kitade, H Kamiya, T Noro, T Kubo, N Nakase, N
Citation
A. Nakagawa et al., Selective ablation of porcine and rabbit liver tissue using radiofrequency: Preclinical study, EUR SURG RE, 31(5), 1999, pp. 371-379
Citations number
18
Categorie Soggetti
Surgery,"Medical Research Diagnosis & Treatment
Journal title
EUROPEAN SURGICAL RESEARCH
ISSN journal
0014312X → ACNP
Volume
31
Issue
5
Year of publication
1999
Pages
371 - 379
Database
ISI
SICI code
0014-312X(199909/10)31:5<371:SAOPAR>2.0.ZU;2-F
Abstract
Temperature changes and their distribution induced by 13.56-MHz radiofreque ncy (RF) heating of agar phantom and porcine and rabbit liver were investig ated. It was possible to produce selective local heating of approximately 5 0 degrees C in the RF field of 2 x 2 x 2 cm(3) of the pig or rabbit liver. Coagulation necrosis after heating became pronounced and the margin between the coagulated lesion and normal tissue became clearer with time. Within 1 week after RF heating at 50 degrees C for 20 min, the coagulated area was replaced selectively and totally by necrotic tissue.