Reaction of rel-(4R,5R)-4-benzoylamino-5-phenyl-3-pyrazolidinone with aliphatic 1,3-dicarbonyl compounds. A 'ring switch' synthesis of rel-(2R,3R)-3-phenyl-3-(pyrazolyl-1)alanine esters

Authors
Svete, J Stanovnik, B
Citation
J. Svete et B. Stanovnik, Reaction of rel-(4R,5R)-4-benzoylamino-5-phenyl-3-pyrazolidinone with aliphatic 1,3-dicarbonyl compounds. A 'ring switch' synthesis of rel-(2R,3R)-3-phenyl-3-(pyrazolyl-1)alanine esters, HETEROCYCLE, 51(9), 1999, pp. 2073-2078
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
51
Issue
9
Year of publication
1999
Pages
2073 - 2078
Database
ISI
SICI code
0385-5414(19990901)51:9<2073:RORWA>2.0.ZU;2-R
Abstract
rel-(2R,3R)-N-Benzoyl-3-phenyl-3-(pyrazolyl-1)alanine esters (5-8) were pre pared by acid-catalysed treatment of rel-(4R,5R)-4-benzoylamino-5-phenyl-3- pyrazolidinone (1) with various aliphatic 1,3-dicarbonyl compounds (2-4).