Synthesis of 6-substituted 5,6,7,12-tetrahydrobenzo[4,5]-cyclohept[b]indol-12-one derivatives

Authors
Mouaddib, A Joseph, B Hasnaoui, A Merour, JY Leonce, S
Citation
A. Mouaddib et al., Synthesis of 6-substituted 5,6,7,12-tetrahydrobenzo[4,5]-cyclohept[b]indol-12-one derivatives, HETEROCYCLE, 51(9), 1999, pp. 2127-2137
Citations number
9
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
51
Issue
9
Year of publication
1999
Pages
2127 - 2137
Database
ISI
SICI code
0385-5414(19990901)51:9<2127:SO65>2.0.ZU;2-Q
Abstract
The synthesis of 6-substituted 5,6,7,12-dihydrobenzo[4,5]cyclohept[b]indole derivatives, through a regioselective alkylation of 1 in position-6, is re ported. The antiproliferative activity of 18 was evaluated.