The regeneration of periodontal structures lost to inflammatory disease is
an elusive yet attainable goal of periodontal therapy. This article reports
the successful treatment of a large periodontal defect using a combination
of demineralized freeze-dried bone allograft (DFDBA) and guided tissue reg
eneration (GTR). The case presents endodontic and mucogingival complication
s in the combined GTR osseous graft technique. The combined techniques used
in this 27-year-old patient achieved a reduction in probing depth, radiogr
aphic evidence of bone fill, and a reduction in clinical mobility.