Histologic observations of periodontal wound healing after treatment with PerioGlas in nonhuman primates

The effect of PerioGlas (synthetic bone particulate) on wound healing of ex perimental palatal periodontal defects in monkeys was evaluated. Chronic pe riodontal defects were created on the palatal aspects of maxillary molars a nd premolars. Open-flap debridement was performed. Experimental sites recei ved PerioGlas, while control sites received no further treatment Histologic measurements were performed on new bone, new cementum, epithelial downgrow th, and recession. Results showed significantly more new cementum and less epithelial downgrowth in the sites that received PerioGlas (P < 0.05). The present results indicate that PerioGlas may enhance periodontal wound heali ng outcomes.