No effect of short-term exposure to GSM-modulated low-power microwaves on benzo(a)pyrene-induced tumours in rat

Purpose: fn view of current interest in the biological effects of amplitude -modulated microwaves arising from the rapid development of mobile communic ations, the effects of low-level microwaves on cancer development were inve stigated using a rat sarcoma model. Materials and methods: Two-month-old female Sprague-Dawley rats were treate d by injection of benzo(a)pyrene and irradiated with GSM (Global System for Mobile)-modulated 900-MHz microwaves in an anechoic chamber at 55 or 200 m u W cm(-2) (75 and 270 mW kg(-1) average whole-body SAR, 2h daily for 2 wee ks). Rats were exposed from day 20, 40 or 75 after carcinogen injection. Ad ditional groups of rats were sham-exposed in a second anechoic chamber. Ant i-phosphatidylinositol autoantibody levels were evaluated in sera to monito r malignant transformation. Results: Microwave exposure had no effect on the development of tumours. No acceleration or delays in tumour onset were observed. Animal survival was not modified and serum autoantibody levels were similar in exposed and sham -exposed groups. Conclusion: Low-level GSM microwave exposure of rat bearing benzo(a)pyrene- induced rumours had no effect on auto-antibody levels, tumour appearance an d survival. The low exposure levels used here correspond to exposure limits for whole-body exposure of humans.