Purpose: The purpose of this study was to examine the clarity of the visual
axis after Nd:YAG laser capsulotomy following cataract extraction and prim
ary intraocular lens implantation in a pediatric population, Methods: A ret
rospective review was performed of all cases of cataract extraction and pri
mary intraocular lens implantation over a period of 5 years, A group of chi
ldren who had been treated by primary surgical posterior capsulotomy and an
terior vitrectomy (Group 1) was used as the "gold standard," with whom the
children treated with Nd:YAG laser capsulotomy (Group 2) were compared. The
groups were studied for the incidence of opacification of the visual axis
after the primary procedure. Results: Data on 78 eyes were reviewed, and 56
eyes met inclusion criteria. Of these, 33 eyes were treated with primary p
osterior capsulotomy and anterior vitrectomy (Group 1) and 23 eyes were tre
ated with Nd:YAG laser capsulotomy (Group 2), One eye (3%) of Group 1 exper
ienced postoperative visual axis reopacification. Thirteen (57%) of 23 eyes
in Group 2 experienced reopacification, requiring retreatment Four eyes (1
7%) treated with Nd:YAG laser required a third treatment. Conclusions: In o
ur series, 57% of patients treated with Nd:YAG laser capsulotomy experience
d reopacification across the anterior hyaloid face. With the removal of the
anterior vitreous at the time of cataract extraction, the scaffolding for
cell migration is removed and reopacification of the visual axis is rarely
seen, For patients in whom slit-lamp capsulotomy is not possible, especiall
y if there is no Nd:YAG laser available for use in the operating room or wh
en loss to follow-up may be an issue, primary posterior capsulotomy and ant
erior vitrectomy should be strongly considered.