This annual review of X-ray fluorescence covers papers published over the p
eriod 1998-1999 that are judged to have made a significant contribution to
this branch of the analytical sciences. The review is both comprehensive in
scope and selective in the choice of contributions included. The scope inc
ludes developments in instrumentation and detectors, matrix correction and
spectrum analysis software, X-ray optics and microfluorescence, synchrotron
XRF, TXRF, portable XRF and on-line applications. Also included is a revie
w of applications, including sample preparation, geological, environmental,
archaeological, forensic, biological, clinical, thin films and chemical st
ate analysis, including speciation. Highlights of this year include further
work in the development of high resolution detector devices based on both
microcalorimeters and superconducting tunnel junction devices. However, the
re continue to be important developments in capillary X-ray optics, portabl
e XRF, on-line applications, TXRF and synchrotron radiation devices. Furthe
rmore, it is noteworthy that XRF continues to make an essential contributio
n in a wide range of applications where the non-destructive, high precision
, simple sample preparation techniques and well-characterised spectrum inte
rpretation and quantification procedures can be used to advantage.