1,3-dipolar cycloaddition reactions of nitrones with unsaturated methylsulfones and substituted crotonic esters

Authors
Charmier, MOJ Moussalli, N Chanet-Ray, J Chou, ST
Citation
Moj. Charmier et al., 1,3-dipolar cycloaddition reactions of nitrones with unsaturated methylsulfones and substituted crotonic esters, J CHEM R-S, (9), 1999, pp. 566-567
Citations number
32
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL RESEARCH-S
ISSN journal
03082342 → ACNP
Issue
9
Year of publication
1999
Pages
566 - 567
Database
ISI
SICI code
0308-2342(199909):9<566:1CRONW>2.0.ZU;2-W
Abstract
The cycloaddition reaction of nitrones to unsaturated methylsulfones and su bstituted crotonic esters gives a sole product or a mixture of tri- or tetr a-substituted isoxazolidines, such that with disubstituted dipolarophiles t he regiochemistry is dependent upon the nitrone and the vicinal electron-wi thdrawing group (CN or CO2Me) but with trisubstituted olefins, regiospecifi c cycloadditions are observed.