In the acute setting, patients with periappendiceal masses generally improv
e with broad-spectrum antibiotics with or without percutaneous catheter dra
inage, but whether or not to perform an interval appendectomy remains contr
oversial. We have analyzed our experience over the past decade, comparing r
esults from interval laparoscopic appendectomy (ILA) and interval open appe
ndectomy (IOA). Medical records were reviewed for 56 patients who initially
presented with the diagnosis of periappendiceal mass or abscess and who su
bsequently underwent interval appendectomy. Data were accumulated for both
the initial hospitalization and interval appendectomy. Comparisons were mad
e between period 1 (1987 to 1993) and period 2 (1994 to 1997). Follow-up da
ta were obtained via telephone conversations with the patients. Patient cha
racteristics with regard to age, sex, and comorbidities did not differ betw
een the ILA and IOA groups. The number of patients undergoing CAT scan incr
eased from 33% to 55%, whereas the initial hospital stay decreased from 7.4
2 to 4.61 days (P <0.001). The percentage of interval appendectomies perfor
med by the laparoscopic method increased from 30% to 85%. The total operati
ng room time did not differ (95 vs. 103 minutes), but the hospital stay was
much shorter in the ILA group (0.55 vs. 3.07 days, P <0.001). There were n
o instances of intra-abdominal or wound infections in either group. In the
later time period the mean hospital stay decreased to 0.38 days, with 59% o
f the operations performed on an outpatient basis. Following ILA, narcotic
pain medication was used for an average of 1.3 days and the reported "time
to return to full activities" was 2.5 days. ILA is a simple and safe proced
ure that can usually be performed on an outpatient basis. Given the minimal
morbidity of the procedure, we believe that ILA should be considered for m
ost patients who initially present with periappendiceal masses.