Epicardial fat may anteriorly produce an echo-free space that can be mistak
en for pericardial fluid. We recently experienced a 67-year-old woman with
prominent epicardial fat which was presented as an echogenic tumor-like mas
s. She underwent open pericardiostomy to relieve large amount of pericardia
l effusion, Operative findings revealed only prominent epicardial fat. Biop
sy of the pericardial and fat tissues revealed an inflammation and normal f
at cells without any malignant cell infiltration.