Pancreatic lipomatosis is characterized by fatty infiltration or replacemen
t of the pancreas, and has been associated with many conditions, We recentl
y experienced two cases of pancreatic lipomatosis in patients with pancreat
ic pseudocyst and a case of lipomatosis in diabetes mellitus, In these pati
ents, abrupt obstruction of the main pancreatic duct with smooth tapering i
s a typical endoscopic retrograde pancreatography (ERP) finding of pancreat
ic lipomatosis and must be differentiated with pancreatic carcinoma.