Calcified lesions of the temporomandibular joint discs obtained from 135 hu
man cadavers were studied. Calcifications were observed in 92 of 250 discs
by soft x-ray radiography. Studies by light and electron microscopy and x-r
ay diffraction revealed that there were two different types of calcificatio
n in the discs: apatite crystal deposition with or without ossification, an
d calcium pyrophosphate dehydrate (CPPD) crystal deposition. Calcifications
were recognized more frequently posteriorly than anteriorly, and were rela
ted to disc perforation. The results of this investigation suggest that dis
c degeneration, which may occur as a result of aging or mechanical stress,
causes calcifications.