Ethylene dicysteine (EC) and ethyl cysteinate dimer (ECD) complexes of Ga(III) and In(III)

Ethylene dicysteine (EC) and ethyl cysteinate dimer (ECD) complexes of Ga-6 7 and In-111 were prepared and the complexation yield and radiochemical pur ity estimated by paper chromatography, paper electrophoresis and solvent ex traction into chloroform. In-111-EC was found to be anionic, whereas In-111 -ECD was neutral. EC complexes of Ga-67 and In-111 were stable upto 6 hours and expectedly less lipophilic than ECD complexes. ECD complexes of Ga-67 and In-111 were unstable in aqueous medium, but highly stable in chloroform . The utility of the work for stabilisation of products as organic extract and the possible role and limitation for the development of new Ga-68 radio pharmaceuticals and of bifunctional chelating agent (BCA) for In-111 are di scussed.