J. Maki et al., Formation of oxalo-substituted etheno derivatives in reactions of mucochloric acid with adenosine, guanosine and cytidine, J CHEM S P1, (20), 1999, pp. 2923-2928
Treatment of the nucleosides adenosine, guanosine and cytidine with mucochl
oric acid in slightly acid aqueous solutions at 37 degrees C affords oxalo-
substituted etheno derivatives of nucleosides (2a, 3a and 4a). The derivati
ves are structurally characterised by UV, H-1 and C-13 NMR spectroscopy and
mass spectrometry. In addition, all the long-range H-1-C-13 couplings are
assigned in the base moieties of the products. A plausible mechanism is pre
sented for the formation of the products.