The prevention of calculus accumulation in exotic animals is a relatively u
nexplored topic. A 6-mo study in ring-tailed lemurs (Lemur catta) and colla
red lemurs (Eulemur fulvus collaris) and two studies in baboons (Papio cyno
cephalus) (7.5 wks and 6.5 mo) tested the benefits of a primate diet coated
with 0.6% sodium hexametaphosphate (HMP) in controlling calculus in these
species using a sequential crossover design. The control regimen was an ide
ntical, but non-HMP-coated, dry primate chow. At study initiation, the prim
ates were given a thorough dental prophylaxis and provided with the control
diet or experimental diet. At the conclusion of the test period, the anima
ls were anesthetized and examined for clinical calculus independently by tw
o examiners. The animals were then given another dental prophylaxis, provid
ed the alternate ration, and the foregoing procedures were repeated. When t
he animals were provided the HMP-coated diet, significant reductions in cal
culus formation of 48-62% were observed in the lemurs and the baboons. No c
linically significant changes were observed in body weights or in blood che
mistry values as a result of ingestion of the HMP-coated regimen.