Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM): A reversible form of encephalopathy

Authors
Caselli, RJ Boeve, BF Scheithauer, BW O'Duffy, JD Hunder, GG
Citation
Rj. Caselli et al., Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM): A reversible form of encephalopathy, NEUROLOGY, 53(7), 1999, pp. 1579-1581
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
53
Issue
7
Year of publication
1999
Pages
1579 - 1581
Database
ISI
SICI code
0028-3878(19991022)53:7<1579:NAIM(A>2.0.ZU;2-Q
Abstract
Five patients, age 54 to 80 years, presented between 3 weeks and 18 months after symptomatic onset of progressive cognitive decline, psychosis, and un steady gait that proved to be due to a steroid-responsive nonvasculitic aut oimmune inflammatory meningoencephalitic syndrome. CSF examination showed e levated immunoglobulin (Ig)G index and IgG synthesis rate in all three pati ents in whom it was checked, and brain biopsy revealed perivascular lymphoc ytic infiltrates without vessel wall invasion.