REPORT OF THE EUROPEAN DNA PROFILING GROUP (EDNAP) - AN INVESTIGATIONOF THE COMPLEX STR LOCI D21S11 AND HUMFIBRA (FGA)

This paper describes a collaborative exercise which was intended to de monstrate whether uniformity of DNA profiling results could be achieve d between European laboratories using two complex short tandem repeat (STR) loci. The loci D21S11 and HUMFIBRA (FGA) were chosen because the y are commonly used by different European laboratories. D21S11 has app roximately 14 common alleles (f>0.001), whereas HUMFIBRA has 19 common alleles. Laboratories were asked to test seven blood stains, one of w hich was a known control, and to report the results to the coordinatin g laboratory. The exercise demonstrated that complex STRs were amenabl e to standardisation. Copyright (C) 1997 Elsevier Science Ireland Ltd.