Low-dose subcutaneous ketamine infusion and morphine tolerance

Authors
Bell, RF
Citation
Rf. Bell, Low-dose subcutaneous ketamine infusion and morphine tolerance, PAIN, 83(1), 1999, pp. 101-103
Citations number
11
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
PAIN
ISSN journal
03043959 → ACNP
Volume
83
Issue
1
Year of publication
1999
Pages
101 - 103
Database
ISI
SICI code
0304-3959(199910)83:1<101:LSKIAM>2.0.ZU;2-M
Abstract
The NMDA receptor has been reported to be involved in opioid tolerance. Adj uvant subcutaneous infusion treatment with (very) low-dose ketamine, a NMDA receptor antagonist, improves analgesia and at the same time appears to re duce morphine tolerance. Three cases are presented. (C) 1999 International Association for the Study of Pain. Published by Elsevier Science B.V.