Comparison of the activities of enzymes related to glycolysis and gluconeogenesis in the liver of dogs and cats

Activities of enzymes related to glucose metabolism were measured in canine and feline liver. There were no significant differences in plasma glucose and immunoreactive insulin concentrations between dogs and cats. Glucokinas e activities were absent in feline liver, however, activities of other glyc olytic enzymes such as hexokinase, phosphofructokinase and pyruvate kinase, were significantly higher than those in canine livers. Activities of rate limiting enzymes of gluconeogenesis such as pyruvate carboxylase, fructose- 1,6-bisphosphatase and glucose-6-phosphatase in feline livers were signific antly higher than those in canine livers. (C) 1999 Harcourt Publishers Limi ted.