D. Lopez-gomez et al., Thrombopenia and acute renal failure following intravenous streptokinase. The role of steroid therapy, REV ESP CAR, 52(10), 1999, pp. 879-881
Proteinuria is common after streptokinase treatment. An immunological mecha
nism in the renal glomerulus has been suggested to explain this side effect
. However, thrombopenia and acute renal failure streptokinase induced are u
ncommon. We present a case of thrombopenia and acute renal failure after st
reptokinase administration for myocardial infarction that improved with ste
roid therapy. Rie discuss the probable pathophysiology of these adverse eff
ects of streptokinase and the potencial usefulness of steroids in its preve
ntion and treatment.