A facile stereospecific synthesis of chiral beta-keto sulfoxides

Authors
Caputo, R Giordano, F Guaragna, A Palumbo, G Pedatella, S
Citation
R. Caputo et al., A facile stereospecific synthesis of chiral beta-keto sulfoxides, TETRAHEDR-A, 10(18), 1999, pp. 3463-3466
Citations number
10
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
18
Year of publication
1999
Pages
3463 - 3466
Database
ISI
SICI code
0957-4166(19990910)10:18<3463:AFSSOC>2.0.ZU;2-#
Abstract
A synthetic strategy has been devised for the preparation of chiral beta-ke to sulfoxides (actually, alpha-vinylsulfinyl ketones) starting from the rea dily available C-6 substituted 2,3-dihydro-1,4-oxathiines. The procedure, w hich is characterized by high yields and excellent enantiomeric excesses, r epresents an improvement in preparation methods for chiral beta-keto sulfox ides. (C) 1999 published by Elsevier Science Ltd. All rights reserved.