Novel applications of chloroperoxidase: enantioselective oxidation of racemic epoxyalcohols

Authors
Kiljunen, E Kanerva, LT
Citation
E. Kiljunen et Lt. Kanerva, Novel applications of chloroperoxidase: enantioselective oxidation of racemic epoxyalcohols, TETRAHEDR-A, 10(18), 1999, pp. 3529-3535
Citations number
22
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
18
Year of publication
1999
Pages
3529 - 3535
Database
ISI
SICI code
0957-4166(19990910)10:18<3529:NAOCEO>2.0.ZU;2-W
Abstract
The CPO-catalysed enantioselective oxidations of racemic glycidol and cis-2 ,3-epoxyhexanol to the corresponding aldehydes were studied using tert-buty l hydroperoxide in the 9:9:1 and 18:1 mixtures of hexane:ethyl acetate:buff er and hexane:buffer, respectively. Temperature and pH (100 mM citrate buff er, pH 4.0-7.0) effects on enantioselectivity in the terms of ee for the le ss reactive alcohol enantiomers with conversion were studied. (C) 1999 Publ ished by Elsevier Science Ltd. All rights reserved.