Enantiomerically pure pyridine and 2,2 '-bipyridine thioethers: new N-S chiral ligands for asymmetric catalysis. Palladium-catalyzed allylic alkylation

Citation
G. Chelucci et al., Enantiomerically pure pyridine and 2,2 '-bipyridine thioethers: new N-S chiral ligands for asymmetric catalysis. Palladium-catalyzed allylic alkylation, TETRAHEDR-A, 10(18), 1999, pp. 3537-3546
Citations number
22
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
18
Year of publication
1999
Pages
3537 - 3546
Database
ISI
SICI code
0957-4166(19990910)10:18<3537:EPPA2'>2.0.ZU;2-A
Abstract
Diastereomeric pure pyridine and 2,2'-bipyridine thioethers, derived from ( +)-camphor, were prepared and assessed in the enantioselective palladium-ca talyzed allylic substitution of 1,3-diphenylprop-2-enyl acetate with dimeth yl malonate. Enantioselectivities of up to 76% were obtained. (C) 1999 Else vier Science Ltd. All rights reserved.