Enantiomerically pure pyridine and 2,2 '-bipyridine thioethers: new N-S chiral ligands for asymmetric catalysis. Palladium-catalyzed allylic alkylation
G. Chelucci et al., Enantiomerically pure pyridine and 2,2 '-bipyridine thioethers: new N-S chiral ligands for asymmetric catalysis. Palladium-catalyzed allylic alkylation, TETRAHEDR-A, 10(18), 1999, pp. 3537-3546
Diastereomeric pure pyridine and 2,2'-bipyridine thioethers, derived from (
+)-camphor, were prepared and assessed in the enantioselective palladium-ca
talyzed allylic substitution of 1,3-diphenylprop-2-enyl acetate with dimeth
yl malonate. Enantioselectivities of up to 76% were obtained. (C) 1999 Else
vier Science Ltd. All rights reserved.