The National Veterinary Reference Laboratory for tuberculosis was founded i
n 1996, The results of studies on the differentiation of mycobacteria by mi
crobiological, biochemical and molecular biological methods from this time
until 1998 are described. Although a number of correlations between the res
ults of the various methods have been observed no satisfactory, systematic
agreement has been achieved. The conclusion is that molecular biological me
thods should be more widely used in future.