Immunoliposomes for the targeted delivery of antitumor drugs

Authors
Mastrobattista, E Koning, GA Storm, G
Citation
E. Mastrobattista et al., Immunoliposomes for the targeted delivery of antitumor drugs, ADV DRUG DE, 40(1-2), 1999, pp. 103-127
Citations number
161
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ADVANCED DRUG DELIVERY REVIEWS
ISSN journal
0169409X → ACNP
Volume
40
Issue
1-2
Year of publication
1999
Pages
103 - 127
Database
ISI
SICI code
0169-409X(19991110)40:1-2<103:IFTTDO>2.0.ZU;2-F
Abstract
This review presents an overview of the field of immunoliposome-mediated ta rgeting of anticancer agents. First, problems that are encountered when imm unoliposomes are used for systemic anticancer drug delivery and potential s olutions are discussed. Second, an update is given of the in vivo results o btained with immunoliposomes in tumor models. Finally, new developments on the utilization of immunoliposomes for the treatment of cancer are highligh ted. (C) 1999 Elsevier Science B.V. All rights reserved.