Endermologie is a motorized rhythmic folding unfolding and suction techniqu
e of the panniculus adiposus. Our study shows that one 40-min Endermologie
session produces no noticeable changes in biological parameters, except for
plasma estradiol levels, which vary significantly, first by decreasing dur
ing the session, then by increasing afterward. Such an Endermologie/estroge
n interaction can be compared to the clinical effects observed in some pati
ents undergoing regular Endermologie treatment: return of menses in amenorr
rheal patients and a trophic effect on skin and subcutaneous connective tis
sue comparable to that observed during postmenopausal hormone replacement t
herapy. Understanding such an interaction with the estrogen metabolism requ
ires additional studies and opens many paths for research on therapeutic ap
plications before and after menopause beyond refinement of the body contour
and improvement of the appearance of the panniculus adiposus.