Determination of methyl isocyanate in air by fluorimetry

Citation
Hy. Wang et al., Determination of methyl isocyanate in air by fluorimetry, ANALYST, 124(9), 1999, pp. 1327-1330
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYST
ISSN journal
00032654 → ACNP
Volume
124
Issue
9
Year of publication
1999
Pages
1327 - 1330
Database
ISI
SICI code
0003-2654(199909)124:9<1327:DOMIIA>2.0.ZU;2-S
Abstract
The fluorimetric determination of methyl isocyanate in air is described. Me thyl isocyanate in air was absorbed with dimethyl sulfoxide and hydrolyzed to form methylamine. Methylamine was reacted with acetylacetone and formald ehyde in pH 5.6 HOAc-NaOAc buffer solution to form N-methyl-2,6-dimethyl-3, 5-diacetyl-1,4-dihydropyridine, which is a fluorescent substance. The measu rement of relative fluorescence intensity was carried out at 474 nm with ex citation at 404 nm. Effects of pH, heating time and foreign ions on the det ermination of methyl isocyanate were examined. The relationship between flu orescence intensity and concentration of methyl isocyanate was linear in th e range 0.00-0.80 mu g ml(-1). The linear regression equation was C = 0.001 I + 0.0092, with a linear regression correlation coefficient of 0.9994. Th e recovery was 98.3-104.5% and the relative standard deviation was 1.5%. Th e method is rapid, simple and highly sensitive, and can be used for the det ermination of methyl isocyanate in air. The results obtained agreed with th ose of an extraction-photometric method.