Determination of nicarbazin in feeds using liquid chromatography-electrospray mass spectrometry

Authors
Cannavan, A Ball, G Kennedy, DG
Citation
A. Cannavan et al., Determination of nicarbazin in feeds using liquid chromatography-electrospray mass spectrometry, ANALYST, 124(10), 1999, pp. 1431-1434
Citations number
8
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYST
ISSN journal
00032654 → ACNP
Volume
124
Issue
10
Year of publication
1999
Pages
1431 - 1434
Database
ISI
SICI code
0003-2654(199910)124:10<1431:DONIFU>2.0.ZU;2-B
Abstract
A method is presented for the determination of the 4,4'-dinitrocarbanilide component of the coccidiostat nicarbazin in animal feeds. Samples are extra cted by shaking with methanol and analysed, without further clean-up, using liquid chromatography-electrospray mass spectrometry. A deuterated form of the analyte is employed as internal standard to improve the repeatability of the method. The method has been validated at levels between 0.1 and 100 mg kg(-1) with internal standard corrected recoveries between 88 and 101% a nd RSD values < 8%.