Graft-versus-myeloma after withdrawal of immunosuppression following allogeneic peripheral stem cell transplantation

Authors
Libura, J Hoffmann, T Passweg, JR Gregor, M Favre, G Tichelli, A Gratwohl, A
Citation
J. Libura et al., Graft-versus-myeloma after withdrawal of immunosuppression following allogeneic peripheral stem cell transplantation, BONE MAR TR, 24(8), 1999, pp. 925-927
Citations number
19
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
24
Issue
8
Year of publication
1999
Pages
925 - 927
Database
ISI
SICI code
0268-3369(199910)24:8<925:GAWOIF>2.0.ZU;2-7
Abstract
There is growing evidence for a graft-versus-myeloma effect following allog eneic stem cell transplantation. We add to this evidence by reporting compl ete remission achieved by withdrawal of immunosuppression in a patient with multiple myeloma progressing after HLA-identical sibling peripheral stem c ell transplantation, De novo chronic graft-versus-host disease coincided wi th the anti-myeloma effect and responded to treatment, The patient remains in complete remission 3 years after transplant.