Neutrophil folliculitis and serum androgen levels

Pruritic folliculitis (PF) is one of the specific dermatoses of pregnancy t he aetiology of which remains unknown. Several theories have been proposed, and the most commonly accepted is that it represents a hormonally induced acne, as seen in patients taking progestogenic steroids. This theory led to the proposition that serum androgen levels may be elevated in this conditi on. and may be causative. We studied a cohort of 125 pregnant women present ing with a variety of pregnancy dermatoses of whom 12 had PE These women we re compared with 138 pregnant control subjects without a pregnancy dermatos is to determine whether serum androgens were elevated. There was no signifi cant elevation of serum androgens in the 12 cases of PE There was an overal l preponderance of male infants among the PF cases and birthweight of the i nfants was found to be reduced compared with those of controls. However, th e outcome of pregnancy in all cases was favourable implying that PF has no adverse effect on foetal wellbeing.