Combination treatment of rheumatoid arthritis with cyclosporine and methotrexate

Authors
Stein, CM Pincus, T
Citation
Cm. Stein et T. Pincus, Combination treatment of rheumatoid arthritis with cyclosporine and methotrexate, CLIN EXP RH, 17(6), 1999, pp. S47-S52
Citations number
38
Categorie Soggetti
Rheumatology,"da verificare
Journal title
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
ISSN journal
0392856X → ACNP
Volume
17
Issue
6
Year of publication
1999
Supplement
18
Pages
S47 - S52
Database
ISI
SICI code
0392-856X(199911/12)17:6<S47:CTORAW>2.0.ZU;2-V
Abstract
In patients with rheumatoid arthritis (RA) not controlled on methotrexate ( MTX) alone, clinical trials have shown that combination therapy with cyclos porine (CSA) and MTX is effective and relatively well tolerated over 12 mon ths. Information regarding the long-term benefits, toxicities and tolerabil ity of this combination therapy in clinical practice, and comparisons with alternative strategies, will determine the utility of the MTX plus CSA comb ination regimen in patients with RA not controlled with a single drug.