Methotrexate and leflunomide combination therapy for patients with active rheumatoid arthritis

Authors
Mroczkowski, PJ Weinblatt, ME Kremer, JM
Citation
Pj. Mroczkowski et al., Methotrexate and leflunomide combination therapy for patients with active rheumatoid arthritis, CLIN EXP RH, 17(6), 1999, pp. S66-S68
Citations number
15
Categorie Soggetti
Rheumatology,"da verificare
Journal title
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
ISSN journal
0392856X → ACNP
Volume
17
Issue
6
Year of publication
1999
Supplement
18
Pages
S66 - S68
Database
ISI
SICI code
0392-856X(199911/12)17:6<S66:MALCTF>2.0.ZU;2-5
Abstract
An open-label, one-year study was conducted to evaluate the safety and clin ical response to leflunomide and methotrexate combination therapy for rheum atoid arthritis. Study results revealed tolerable safety, no significant ph armacokinetic interactions between methotrexate and leflunomide, and sugges ted improved clinical reponse with combination therapy.