Increased I-131 uptake in local recurrence and distant metastases after second treatment with retinoic acid

Authors
Koerber, C Schmutzler, C Rendl, J Koehrle, J Griesser, H Simon, D Reiners, C
Citation
C. Koerber et al., Increased I-131 uptake in local recurrence and distant metastases after second treatment with retinoic acid, CLIN NUCL M, 24(11), 1999, pp. 849-851
Citations number
2
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
CLINICAL NUCLEAR MEDICINE
ISSN journal
03639762 → ACNP
Volume
24
Issue
11
Year of publication
1999
Pages
849 - 851
Database
ISI
SICI code
0363-9762(199911)24:11<849:IIUILR>2.0.ZU;2-C
Abstract
We present a case of increased I-131 uptake in a patient with papillary thy roid carcinoma with local recurrence and distant metastases after a second treatment with retinoic acid as a sign of redifferentiation of the tumor ce lls. When fine-needle aspiration cytology before and after a second course of retinoic acid treatment were compared, signs of tumor cell redifferentia tion were found, This was accompanied by biochemical reexpression of thyroi d marker proteins.