Effects of VDT pulsed magnetic fields on gap junctional intercellular communication

Chinese hamster lung (CHL) cells were irradiated for 24 h with 15.6-KHz pul sed magnetic field (PMF) at 200 mu T peak to peak and/or 12-O-tetradecanoyl phorbol- 13-acetate (TPA; 5 ng/ml). Lucifer dye was inserted into the CHL c ells by iontophoretic injection. The numbers of dye-coupled cells around th e injected cell were counted to determine the function of gap junctional in tercellular communication (GJIC). The results showed that TPA significantly suppressed GJIC compared with the control group (p < 0.01), but video disp lay terminal pulsed magnetic fields alone or with TPA did not diminish or e nhance suppression by TPA.