Adrenoleukodystrophy associated with vitiligo and ulcerative colitis

Authors
Sawaya, RA Mourad, FH Najjar, S Mikati, M Raymond, GV
Citation
Ra. Sawaya et al., Adrenoleukodystrophy associated with vitiligo and ulcerative colitis, EUR NEUROL, 42(3), 1999, pp. 169-172
Citations number
22
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
EUROPEAN NEUROLOGY
ISSN journal
00143022 → ACNP
Volume
42
Issue
3
Year of publication
1999
Pages
169 - 172
Database
ISI
SICI code
0014-3022(1999)42:3<169:AAWVAU>2.0.ZU;2-V
Abstract
Adrenoleukodystrophy (ALD) is an X-linked inherited disorder of lipid metab olism usually presenting in childhood or early adolescence. It is a progres sive disease with symptoms of adrenal insufficiency and central nervous sys tem demyelination. The pathology results from the accumulation of very long -chain fatty acids and an inflammatory reaction in the brain white matter. We report a case of ALD associated with adrenal insufficiency and two autoi mmune diseases: vitiligo and ulcerative colitis.